Pharmaceutical Biotechnology — MCQs Biology

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1. Pharmaceutical biotechnology involves:
(A) Using biological systems to produce drugs and therapeutic products
(B) Producing plastics from petroleum
(C) Mechanical engineering of machines
(D) Fermenting alcohol only

2. Recombinant insulin is produced using:
(A) Plants only
(B) Humans only
(C) E. coli or yeast
(D) Fungi only

3. Monoclonal antibodies are produced using:
(A) Restriction enzymes
(B) PCR
(C) Hybridoma technology
(D) CRISPR

4. Human growth hormone (HGH) can be produced by:
(A) Fermentation of yeast only
(B) Chemical synthesis only
(C) Extraction from human pituitary glands only
(D) Recombinant DNA technology in bacterial systems

5. Vaccines produced using recombinant DNA technology are called:
(A) Recombinant vaccines
(B) Attenuated vaccines only
(C) Inactivated vaccines only
(D) Synthetic antibiotics

6. Erythropoietin used to treat anemia is produced by:
(A) Plant cells only
(B) Fermentation of yeast only
(C) Extraction from blood only
(D) Recombinant mammalian cell culture

7. Antisense therapy involves:
(A) Using complementary nucleic acid sequences to block gene expression
(B) Protein denaturation
(C) Alcohol fermentation
(D) Enzyme immobilization

8. RNA interference (RNAi) is used to:
(A) Silence specific genes
(B) Amplify DNA
(C) Produce antibiotics
(D) Produce insulin

9. Interferons are used in:
(A) Citric acid production
(B) Antibiotic production
(C) Alcohol fermentation
(D) Antiviral therapies

10. Tissue plasminogen activator (tPA) is used for:
(A) Producing insulin
(B) Lowering cholesterol
(C) Treating infections
(D) Dissolving blood clots

11. Pharmaceutical enzymes like streptokinase are used for:
(A) Alcohol fermentation
(B) Thrombolytic therapy
(C) Citric acid production
(D) DNA sequencing

12. Recombinant vaccines for hepatitis B are produced in:
(A) Mammalian cells only
(B) Bacterial cells only
(C) Yeast cells
(D) Plant cells only

13. Monoclonal antibodies can be used for:
(A) Cancer therapy, autoimmune diseases, and diagnostics
(B) Alcohol production only
(C) Citric acid fermentation only
(D) DNA sequencing

14. Pharmacogenomics studies:
(A) DNA sequencing only
(B) Protein synthesis
(C) How genes affect drug response
(D) RNA transcription only

15. Biopharmaceuticals include:
(A) Proteins, vaccines, hormones, and antibodies produced using biotechnology
(B) Only chemical drugs
(C) Only antibiotics
(D) Only vitamins

16. Recombinant DNA technology is used in pharmaceutical biotechnology for:
(A) DNA extraction only
(B) Mechanical engineering only
(C) Producing therapeutic proteins and hormones
(D) Fermenting alcohol only

17. Human interferon used in antiviral therapy is produced by:
(A) Chemical synthesis only
(B) Recombinant mammalian or bacterial cells
(C) Plant cells only
(D) Yeast fermentation only

18. Pharmaceutical biotechnology helps in:
(A) Producing plastics only
(B) Producing safer, more effective therapeutic products
(C) DNA sequencing only
(D) Industrial enzymes only

19. Recombinant tissue plasminogen activator (tPA) is used to treat:
(A) Viral infections only
(B) Diabetes only
(C) Bacterial infections only
(D) Myocardial infarction and stroke

20. Biopharmaceutical drugs are generally:
(A) Extracted from metals
(B) Synthesized chemically only
(C) Produced by living cells or organisms
(D) Produced mechanically

21. Recombinant vaccines avoid:
(A) Alcohol fermentation
(B) Protein synthesis
(C) Using live pathogens
(D) Enzyme production

22. Pharmacogenetics helps in:
(A) Fermentation only
(B) DNA sequencing only
(C) Protein denaturation
(D) Personalizing drug therapy based on genetic profile

23. Erythropoietin stimulates:
(A) Insulin production
(B) White blood cell production only
(C) Platelet production only
(D) Red blood cell production

24. Therapeutic antibodies target:
(A) Lipids only
(B) Sugars only
(C) Specific antigens in cancer or autoimmune diseases
(D) DNA only

25. Pharmaceutical biotechnology uses cell cultures to:
(A) Produce plastics only
(B) Produce recombinant proteins, vaccines, and antibodies
(C) Sequence DNA only
(D) Produce ethanol only

26. mRNA vaccines work by:
(A) Blocking DNA replication
(B) Delivering DNA into the nucleus
(C) Delivering protein antigens only
(D) Delivering mRNA to cells to produce viral proteins and induce immunity

27. Gene therapy can be used to treat:
(A) Viral infections only
(B) Bacterial infections only
(C) Genetic disorders
(D) Alcohol dependence only

28. Pharmaceutical biotechnology reduces:
(A) Risk of contamination in drug production
(B) DNA replication only
(C) RNA transcription only
(D) Protein denaturation only

29. Recombinant vaccines for COVID-19 include:
(A) Only inactivated vaccines
(B) Only live attenuated vaccines
(C) mRNA vaccines and viral vector vaccines
(D) Only protein subunit vaccines

30. Insulin analogs produced by recombinant DNA are used to treat:
(A) Bacterial infections only
(B) Cancer only
(C) Viral infections only
(D) Diabetes mellitus

31. Biopharmaceutical production often requires:
(A) Mammalian, bacterial, or yeast cell cultures
(B) Metal extraction
(C) Chemical oxidation only
(D) Alcohol fermentation only

32. Interleukins used as therapeutic agents are:
(A) Enzymes only
(B) Cytokines produced by recombinant DNA technology
(C) Proteins from plants only
(D) DNA fragments only

33. Pharmaceutical biotechnology ensures drugs are:
(A) Safe, effective, and reproducible
(B) Toxic and unstable
(C) Produced mechanically only
(D) Produced chemically only

34. Therapeutic proteins like clotting factors are produced in:
(A) Recombinant mammalian cells
(B) Yeast only
(C) Bacteria only
(D) Plants only

35. Biopharmaceuticals can be:
(A) Proteins, hormones, vaccines, and monoclonal antibodies
(B) Only chemical drugs
(C) Only antibiotics
(D) Only vitamins

36. Recombinant vaccines are safer because they:
(A) Are chemically toxic
(B) Require live pathogen cultures
(C) Do not contain live pathogens
(D) Produce heavy metals

37. Pharmaceutical biotechnology uses:
(A) Fermentation only
(B) Chemical synthesis only
(C) Mechanical devices only
(D) Genetic engineering, cell culture, and protein purification

38. Biopharmaceuticals include:
(A) Only antibiotics
(B) Only synthetic chemicals
(C) Recombinant hormones and cytokines
(D) Only vaccines

39. Pharmacogenomics helps to:
(A) Extract DNA only
(B) Produce antibiotics
(C) Ferment alcohol only
(D) Tailor drug therapy to individual genetic profiles

40. Therapeutic monoclonal antibodies can be used to treat:
(A) Alcohol dependence only
(B) Diabetes only
(C) Viral infections only
(D) Cancer and autoimmune diseases

41. Recombinant DNA technology in pharmaceutical biotechnology helps in:
(A) Producing plastics only
(B) Producing proteins with desired modifications
(C) DNA extraction only
(D) Protein denaturation only

42. Pharmaceutical biotechnology reduces:
(A) Protein denaturation only
(B) DNA replication only
(C) RNA transcription only
(D) Side effects and variability in drug production

43. Gene therapy can involve:
(A) Fermentation only
(B) Extracting proteins only
(C) Introducing functional genes into patients’ cells
(D) Chemical synthesis only

44. Recombinant interferons are used to treat:
(A) Diabetes only
(B) Viral infections and certain cancers
(C) Hypertension only
(D) Bacterial infections only

45. Biopharmaceuticals are produced in:
(A) Mechanical systems only
(B) Metals only
(C) Chemicals only
(D) Living cells using recombinant DNA technology

46. Pharmacogenomics helps avoid:
(A) Fermentation only
(B) Protein denaturation only
(C) DNA extraction only
(D) Adverse drug reactions

47. Recombinant clotting factors are used for treating:
(A) Hypertension only
(B) Diabetes only
(C) Hemophilia
(D) Viral infections only

48. mRNA vaccines induce immunity by:
(A) Delivering DNA only
(B) Producing viral proteins inside host cells
(C) Delivering protein antigens only
(D) Blocking transcription

49. Therapeutic cytokines produced by biotechnology include:
(A) Only proteins from plants
(B) Only enzymes
(C) Only antibiotics
(D) Interferons and interleukins

50. Pharmaceutical biotechnology enhances drug development by:
(A) Producing plastics only
(B) Reducing production time and improving efficacy
(C) Fermenting alcohol only
(D) DNA sequencing only