1. Pharmaceutical biotechnology involves:
(A) Using biological systems to produce drugs and therapeutic products
(B) Producing plastics from petroleum
(C) Mechanical engineering of machines
(D) Fermenting alcohol only
2. Recombinant insulin is produced using:
(A) Plants only
(B) Humans only
(C) E. coli or yeast
(D) Fungi only
3. Monoclonal antibodies are produced using:
(A) Restriction enzymes
(B) PCR
(C) Hybridoma technology
(D) CRISPR
4. Human growth hormone (HGH) can be produced by:
(A) Fermentation of yeast only
(B) Chemical synthesis only
(C) Extraction from human pituitary glands only
(D) Recombinant DNA technology in bacterial systems
5. Vaccines produced using recombinant DNA technology are called:
(A) Recombinant vaccines
(B) Attenuated vaccines only
(C) Inactivated vaccines only
(D) Synthetic antibiotics
6. Erythropoietin used to treat anemia is produced by:
(A) Plant cells only
(B) Fermentation of yeast only
(C) Extraction from blood only
(D) Recombinant mammalian cell culture
7. Antisense therapy involves:
(A) Using complementary nucleic acid sequences to block gene expression
(B) Protein denaturation
(C) Alcohol fermentation
(D) Enzyme immobilization
8. RNA interference (RNAi) is used to:
(A) Silence specific genes
(B) Amplify DNA
(C) Produce antibiotics
(D) Produce insulin
9. Interferons are used in:
(A) Citric acid production
(B) Antibiotic production
(C) Alcohol fermentation
(D) Antiviral therapies
10. Tissue plasminogen activator (tPA) is used for:
(A) Producing insulin
(B) Lowering cholesterol
(C) Treating infections
(D) Dissolving blood clots
11. Pharmaceutical enzymes like streptokinase are used for:
(A) Alcohol fermentation
(B) Thrombolytic therapy
(C) Citric acid production
(D) DNA sequencing
12. Recombinant vaccines for hepatitis B are produced in:
(A) Mammalian cells only
(B) Bacterial cells only
(C) Yeast cells
(D) Plant cells only
13. Monoclonal antibodies can be used for:
(A) Cancer therapy, autoimmune diseases, and diagnostics
(B) Alcohol production only
(C) Citric acid fermentation only
(D) DNA sequencing
14. Pharmacogenomics studies:
(A) DNA sequencing only
(B) Protein synthesis
(C) How genes affect drug response
(D) RNA transcription only
15. Biopharmaceuticals include:
(A) Proteins, vaccines, hormones, and antibodies produced using biotechnology
(B) Only chemical drugs
(C) Only antibiotics
(D) Only vitamins
16. Recombinant DNA technology is used in pharmaceutical biotechnology for:
(A) DNA extraction only
(B) Mechanical engineering only
(C) Producing therapeutic proteins and hormones
(D) Fermenting alcohol only
17. Human interferon used in antiviral therapy is produced by:
(A) Chemical synthesis only
(B) Recombinant mammalian or bacterial cells
(C) Plant cells only
(D) Yeast fermentation only
18. Pharmaceutical biotechnology helps in:
(A) Producing plastics only
(B) Producing safer, more effective therapeutic products
(C) DNA sequencing only
(D) Industrial enzymes only
19. Recombinant tissue plasminogen activator (tPA) is used to treat:
(A) Viral infections only
(B) Diabetes only
(C) Bacterial infections only
(D) Myocardial infarction and stroke
20. Biopharmaceutical drugs are generally:
(A) Extracted from metals
(B) Synthesized chemically only
(C) Produced by living cells or organisms
(D) Produced mechanically
21. Recombinant vaccines avoid:
(A) Alcohol fermentation
(B) Protein synthesis
(C) Using live pathogens
(D) Enzyme production
22. Pharmacogenetics helps in:
(A) Fermentation only
(B) DNA sequencing only
(C) Protein denaturation
(D) Personalizing drug therapy based on genetic profile
23. Erythropoietin stimulates:
(A) Insulin production
(B) White blood cell production only
(C) Platelet production only
(D) Red blood cell production
24. Therapeutic antibodies target:
(A) Lipids only
(B) Sugars only
(C) Specific antigens in cancer or autoimmune diseases
(D) DNA only
25. Pharmaceutical biotechnology uses cell cultures to:
(A) Produce plastics only
(B) Produce recombinant proteins, vaccines, and antibodies
(C) Sequence DNA only
(D) Produce ethanol only
26. mRNA vaccines work by:
(A) Blocking DNA replication
(B) Delivering DNA into the nucleus
(C) Delivering protein antigens only
(D) Delivering mRNA to cells to produce viral proteins and induce immunity
27. Gene therapy can be used to treat:
(A) Viral infections only
(B) Bacterial infections only
(C) Genetic disorders
(D) Alcohol dependence only
28. Pharmaceutical biotechnology reduces:
(A) Risk of contamination in drug production
(B) DNA replication only
(C) RNA transcription only
(D) Protein denaturation only
29. Recombinant vaccines for COVID-19 include:
(A) Only inactivated vaccines
(B) Only live attenuated vaccines
(C) mRNA vaccines and viral vector vaccines
(D) Only protein subunit vaccines
30. Insulin analogs produced by recombinant DNA are used to treat:
(A) Bacterial infections only
(B) Cancer only
(C) Viral infections only
(D) Diabetes mellitus
31. Biopharmaceutical production often requires:
(A) Mammalian, bacterial, or yeast cell cultures
(B) Metal extraction
(C) Chemical oxidation only
(D) Alcohol fermentation only
32. Interleukins used as therapeutic agents are:
(A) Enzymes only
(B) Cytokines produced by recombinant DNA technology
(C) Proteins from plants only
(D) DNA fragments only
33. Pharmaceutical biotechnology ensures drugs are:
(A) Safe, effective, and reproducible
(B) Toxic and unstable
(C) Produced mechanically only
(D) Produced chemically only
34. Therapeutic proteins like clotting factors are produced in:
(A) Recombinant mammalian cells
(B) Yeast only
(C) Bacteria only
(D) Plants only
35. Biopharmaceuticals can be:
(A) Proteins, hormones, vaccines, and monoclonal antibodies
(B) Only chemical drugs
(C) Only antibiotics
(D) Only vitamins
36. Recombinant vaccines are safer because they:
(A) Are chemically toxic
(B) Require live pathogen cultures
(C) Do not contain live pathogens
(D) Produce heavy metals
37. Pharmaceutical biotechnology uses:
(A) Fermentation only
(B) Chemical synthesis only
(C) Mechanical devices only
(D) Genetic engineering, cell culture, and protein purification
38. Biopharmaceuticals include:
(A) Only antibiotics
(B) Only synthetic chemicals
(C) Recombinant hormones and cytokines
(D) Only vaccines
39. Pharmacogenomics helps to:
(A) Extract DNA only
(B) Produce antibiotics
(C) Ferment alcohol only
(D) Tailor drug therapy to individual genetic profiles
40. Therapeutic monoclonal antibodies can be used to treat:
(A) Alcohol dependence only
(B) Diabetes only
(C) Viral infections only
(D) Cancer and autoimmune diseases
41. Recombinant DNA technology in pharmaceutical biotechnology helps in:
(A) Producing plastics only
(B) Producing proteins with desired modifications
(C) DNA extraction only
(D) Protein denaturation only
42. Pharmaceutical biotechnology reduces:
(A) Protein denaturation only
(B) DNA replication only
(C) RNA transcription only
(D) Side effects and variability in drug production
43. Gene therapy can involve:
(A) Fermentation only
(B) Extracting proteins only
(C) Introducing functional genes into patients’ cells
(D) Chemical synthesis only
44. Recombinant interferons are used to treat:
(A) Diabetes only
(B) Viral infections and certain cancers
(C) Hypertension only
(D) Bacterial infections only
45. Biopharmaceuticals are produced in:
(A) Mechanical systems only
(B) Metals only
(C) Chemicals only
(D) Living cells using recombinant DNA technology
46. Pharmacogenomics helps avoid:
(A) Fermentation only
(B) Protein denaturation only
(C) DNA extraction only
(D) Adverse drug reactions
47. Recombinant clotting factors are used for treating:
(A) Hypertension only
(B) Diabetes only
(C) Hemophilia
(D) Viral infections only
48. mRNA vaccines induce immunity by:
(A) Delivering DNA only
(B) Producing viral proteins inside host cells
(C) Delivering protein antigens only
(D) Blocking transcription
49. Therapeutic cytokines produced by biotechnology include:
(A) Only proteins from plants
(B) Only enzymes
(C) Only antibiotics
(D) Interferons and interleukins
50. Pharmaceutical biotechnology enhances drug development by:
(A) Producing plastics only
(B) Reducing production time and improving efficacy
(C) Fermenting alcohol only
(D) DNA sequencing only