Cytogenetics — MCQs Biology 50 min Score: 0 Attempted: 0/50 Subscribe 1. Cytogenetics is the branch of biology that deals with the study of: (A) Cell metabolism (B) Tissue organization (C) Chromosomes and their behavior (D) Molecular enzymes 2. The term chromosome was coined by: (A) Waldeyer (B) Fleming (C) Sutton (D) Mendel 3. Chromosomes are best visible during: (A) Interphase (B) Prophase (C) Metaphase (D) Telophase 4. The constricted region of a chromosome is called: (A) Chromatid (B) Telomere (C) Centromere (D) Kinetochore 5. The ends of chromosomes are known as: (A) Telomeres (B) Chromomeres (C) Centromeres (D) Origins 6. A chromosome with the centromere in the middle is called: (A) Acrocentric (B) Metacentric (C) Telocentric (D) Submetacentric 7. Chromosomes having centromere near one end are: (A) Metacentric (B) Submetacentric (C) Acrocentric (D) Holocentric 8. A chromosome without a centromere is known as: (A) Dicentric (B) Polycentric (C) Acentric (D) Telocentric 9. The number of chromosomes in somatic human cells is: (A) 23 (B) 44 (C) 46 (D) 48 10. Haploid chromosome number in humans is: (A) 23 (B) 22 (C) 44 (D) 46 11. The complete set of chromosomes of an organism is called: (A) Genome (B) Nucleotype (C) Idiogram (D) Karyotype 12. Diagrammatic representation of chromosomes arranged in order is called: (A) Idiogram (B) Nucleolus (C) Genome (D) Chromatid 13. Chromosomal study using staining techniques is known as: (A) Karyotyping (B) Autoradiography (C) Gene mapping (D) PCR 14. G-banding technique is mainly used to: (A) Count ribosomes (B) Identify chromosome regions (C) Detect proteins (D) Observe RNA 15. The nucleolar organizer region (NOR) is associated with: (A) mRNA synthesis (B) rRNA synthesis (C) tRNA synthesis (D) DNA replication 16. Secondary constrictions are found at: (A) Telomeres (B) Centromeres (C) NOR regions (D) Chromatids 17. Polyploidy refers to the presence of: (A) Extra genes (B) More than two sets of chromosomes (C) Extra chromosomes (D) Mutated DNA 18. Aneuploidy involves: (A) Change in gene sequence (B) Duplication of genome (C) Change in chromosome sets (D) Loss or gain of one or few chromosomes 19. Down syndrome is caused by: (A) Monosomy X (B) Trisomy 21 (C) Trisomy 18 (D) Polyploidy 20. Turner syndrome individuals have chromosome complement: (A) XO (B) XY (C) XX (D) XXX 21. Klinefelter syndrome is represented by: (A) XO (B) XXY (C) XXX (D) XYY 22. Structural changes in chromosomes include: (A) Polyploidy (B) Deletion (C) Aneuploidy (D) Trisomy 23. Loss of a chromosome segment is called: (A) Duplication (B) Inversion (C) Translocation (D) Deletion 24. Reversal of chromosome segment is termed: (A) Duplication (B) Deletion (C) Translocation (D) Inversion 25. Exchange of segments between non-homologous chromosomes is called: (A) Duplication (B) Translocation (C) Inversion (D) Deletion 26. Chromosome duplication results in: (A) Loss of genes (B) Chromosome loss (C) Gene inversion (D) Extra gene copies 27. A chromosome with two centromeres is known as: (A) Acentric (B) Dicentric (C) Polycentric (D) Holocentric 28. Holocentric chromosomes have: (A) No centromere (B) One centromere (C) Diffuse centromere (D) Centromere at ends 29. Chromosomal aberrations can be detected using: (A) Karyotyping (B) Light microscopy (C) PCR (D) Western blot 30. Barr body represents: (A) Active X chromosome (B) Autosome (C) Y chromosome (D) Inactive X chromosome 31. Number of Barr bodies equals: (A) Number of X chromosomes (B) Y chromosomes (C) X chromosomes minus one (D) Autosomes 32. Chromatin that stains lightly is called: (A) Euchromatin (B) Heterochromatin (C) Chromomere (D) Kinetochore 33. Highly condensed and inactive chromatin is known as: (A) Euchromatin (B) Heterochromatin (C) Chromatid (D) Centromere 34. Chromosome pairing occurs during: (A) Mitosis (B) Meiosis I (C) Meiosis II (D) Interphase 35. Synapsis occurs during which stage? (A) Leptotene (B) Diplotene (C) Pachytene (D) Zygotene 36. Crossing over takes place during: (A) Leptotene (B) Pachytene (C) Zygotene (D) Diakinesis 37. Visible evidence of crossing over is called: (A) Synapsis (B) Tetrad (C) Chiasma (D) Bivalent 38. A bivalent consists of: (A) One chromosome (B) Two chromatids (C) Four cells (D) Two homologous chromosomes 39. Tetrad formation occurs due to: (A) DNA replication (B) Chromosome duplication (C) Pairing of homologous chromosomes (D) Cell division 40. Sex chromosomes in humans are: (A) XX and XY (B) XY only (C) XX only (D) XO 41. Autosomes in humans are: (A) 24 pairs (B) 23 pairs (C) 21 pairs (D) 22 pairs 42. The smallest human chromosome is: (A) Chromosome 1 (B) Chromosome Y (C) Chromosome X (D) Chromosome 21 43. Polytene chromosomes are found in: (A) Human neurons (B) Plant roots (C) Liver cells (D) Salivary glands of Drosophila 44. Lampbrush chromosomes are observed during: (A) Oogenesis (B) Spermatogenesis (C) Mitosis (D) Fertilization 45. Satellite chromosomes possess: (A) Extra centromere (B) Extra genes (C) Two telomeres (D) Secondary constriction 46. Kinetochore is associated with: (A) Centromere (B) Telomere (C) Chromatid (D) Chromomere 47. Chromosomal mutations are also called: (A) Gene mutations (B) Structural aberrations (C) Point mutations (D) Silent mutations 48. Numerical chromosome changes affect: (A) Gene sequence (B) Chromosome number (C) Protein structure (D) Enzyme activity 49. Euploid condition refers to: (A) Normal chromosome sets (B) Abnormal chromosome number (C) Missing chromosome (D) Extra chromosome 50. Cytogenetic analysis is mainly useful for studying: (A) Metabolic pathways (B) Protein synthesis (C) Enzyme kinetics (D) Chromosomal abnormalities